one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity linked to bortezomib, a proteasome inhibitor used in the therapy of multiple myeloma. Its synthesis or research is vital for ensuring the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-1): A key compound from the synthesis of imatinib, a drug that targets precise sorts of cancer, like Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats many cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their research is crucial for optimizing the production approach and ensuring superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is applied to take care of breast cancer, and these intermediates are linked to its creation.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist used in the therapy of breast most cancers. Many intermediates assist in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 4S)-3-Hydroxy-4-phenyl-2-azetidinone 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug successful in dealing with cancers including ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal cancer and compact cell lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is involved with the synthesis of adamantane derivatives, that have numerous applications, together with antiviral Houses.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind two diabetic issues that inhibits the enzyme DPP-4 to manage blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, which can be Employed in foods, pharmaceutical, and CAS 702-82-9 industrial applications.
Canagliflozin Intermediate two: A precursor inside the synthesis of canagliflozin, a medication employed to manage variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).